The Difference Between Suboxone and Sublocade

Know the difference between suboxone and sublocade

Suboxone and Sublocade are two commonly used medications in the treatment of opioid addiction. Both medications contain buprenorphine, a partial opioid agonist, and are used to reduce withdrawal symptoms and cravings in people recovering from opioid addiction. However, several key differences between the two medications are important to understand.


The primary difference between Suboxone and Sublocade is their formulation. Suboxone is a sublingual film or tablet that is placed under the tongue and allowed to dissolve. The medication is absorbed through the lining of the mouth and into the bloodstream. On the other hand, Sublocade is a monthly injection that is given by a healthcare provider. The medication is slowly released into the body over time.


Another important difference between Suboxone and Sublocade is their dosing. Suboxone is typically taken once or twice a day, depending on the individual’s needs. The dosage can be adjusted based on the severity of the withdrawal symptoms and cravings. In contrast, Sublocade is administered once a month by a healthcare provider. The dose is determined based on the individual’s tolerance to buprenorphine and their overall health.


Adherence is a critical factor in the success of any addiction treatment. Suboxone requires daily self-administration, which can be challenging for some individuals. On the other hand, Sublocade is administered by a healthcare provider once a month, which may improve adherence for some patients.

Side Effects

Both Suboxone and Sublocade can cause side effects, although the specific side effects may differ between the two medications. Common side effects of Suboxone include headache, nausea, vomiting, constipation, and difficulty sleeping. Common side effects of Sublocade include injection site reactions, nausea, headache, and constipation.

Duration of Treatment

The duration of treatment with Suboxone and Sublocade can also differ. Suboxone is typically used as a maintenance treatment for opioid addiction and can be continued for as long as the individual needs it. In contrast, Sublocade is typically used as a short-term treatment, with most individuals transitioning to another form of buprenorphine maintenance therapy after a few months.


Overall, both Suboxone and Sublocade are effective medications for the treatment of opioid addiction. However, they differ in their formulation, dosing, adherence, side effects, and duration of treatment. It’s important to work with a healthcare provider to determine which medication is best for your individual needs and to closely follow the prescribed treatment plan to achieve the best possible outcome.


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A medical professional who specializes in treating individuals with opioid dependence or addiction is a Suboxone doctor. Suboxone, a medication containing a combination of buprenorphine

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